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Looking for  agonists ?
 antagonists ?
 reverse agonists ?
Novaleads addresses screening needs for GPCR and RTK therapeutic targets with four functional assays that exploit cell signalling pathway protein translocation events.
   CYME-PKA *
 CYME-PKC
 CYME-Raf
 CYME-Akt
Four live-cell translocation assays for GPCR and RTK screening programmes
* since the cAMP pathway does not involve protein translocation, a modified PKA able to translocate between the cytopasm and plasma membrane has been constructed (W0 03/085405)